The Center for Foodborne Illness Research & Prevention and Consumer Federation of America comment on the Food Safety Inspection Service’s (FSIS) proposal to collect data about consumer knowledge and perceptions related to the safe handling and preparation of raw or partially cooked meat and poultry products. FSIS will use this information to determine if a revision of the mandatory Safe Handling Instructions (SHI) label for meat and poultry products is warranted. CFI and CFA agree that investigating the idea of revising the SHI label is warranted and encourages the approval of FSIS’ plans to investigate this issue. These are initial comments and should not be considered complete.